The Oren Levy Lab is a research laboratory in the Department of Anesthesiology at Mass General Brigham. Located at Brigham and Women’s Hospital, this lab focuses on advancing stem cell bioengineering to address some of the most urgent unmet clinical needs. By integrating stem cell biology, tissue engineering, and regenerative medicine, we develop innovative therapeutic strategies to restore function in complex diseases and injuries. Our current research efforts with our partners span a range of conditions with a significant global impact and room for more effective treatments. Through interdisciplinary science and translational research, we strive to create next‑generation regenerative therapies that can meaningfully improve patient outcomes.
Current Research Areas
We are focused on developing stem cell bioengineering strategies to tackle unmet clinical needs.
Obesity
Obesity affects more than 70% of US adults, creating an enormous health and economic burden, yet effective non-invasive treatments are limited.
Acute burn trauma care
Burn injuries affect 11 million people every year worldwide. There is a major need to expedite the slow healing of deep burn injuries.
Inflammatory bowel disease
Inflammatory bowel disease affects 1 in 100 people in the US, yet current treatment strategies fail to address fundamental intestinal epithelial function issues.
Sensorineural hearing loss
Sensorineural hearing loss affects over 1 billion people worldwide, and there is currently no cure or drug available to induce hair cell growth.
Xerostomia (dry mouth)
Xerostomia affects 2 billion people worldwide, and there are currently no effective or disease-modifying treatments for dry mouth (only temporary symptomatic relief).
Our Partners
